Title: Architecture of Mesoscale Networks in the Primate Brain

 Abstract:

 Human and nonhuman primate brains are characterized by submillimeter functional domains. However, little is known about networks based on such functional nodes. We have developed new methods to stimulate single submillimeter nodes in macaque monkey cortical and subcortical sites, and to map, at local and whole brain scale, the mesoscale networks activated by single node stimulation. Our data show resulting networks are topographic, specific and sparse. The data also suggest the presence of canonical intra-areal and inter-areal micro-network basis vectors. Ultimately, the goal is to understand how connectional architecture in the primate brain underlies primate behavioral repertoires and intelligence.